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. 2022 Oct 5;13:1007274. doi: 10.3389/fphar.2022.1007274

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Copyright © 2022 He, Yang, Zhang, Li, Li, Pu, He, Zhang, Yang, Yu, Qi, Li and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular docking analysis. (A‒B) Molecular docking of polyporenic acid C and Poricoic acid B to farnesoid X receptor (FXR). (C-D) Molecular docking of polyporenic acid C and Poricoic acid B to peroxisome proliferator-activated receptor α (PPARA, PPARα). (E‒G) Molecular docking of poricoic acid B to aromatase (CYP19A1), fatty acid synthase (FASN), and glucocorticoid receptor (NR3C1). (H‒J) Molecular docking of polyporenic acid C to CYP19A1, FASN, and NR3C1. CYP19A1, aromatase; NR3C1, Glucocorticoid receptor.