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. 2022 Oct 5;13:1023237. doi: 10.3389/fphys.2022.1023237

FIGURE 1.

FIGURE 1

RNA transcript changes of palmitoylating and depalmitoylating enzymes and accessory proteins in heart failure. Hahn and Knutsdottir et al. (2020) performed RNA sequencing on biopsies from heart failure patients with preserved ejection fraction (HFpEF, n = 41), reduced ejection fraction (HFrEF, n = 30) and donor controls (n = 24). Abundance of transcripts of palmitoylating and depalmitoylating enzymes, including 23 zDHHC-palmitoyl acyltransferases, as well as accessory proteins and proteins involved in fatty acid and fatty acyl-CoA synthesis, were investigated in the available data. HFpEF and HFrEF are plotted relative to control (normalised to 1) in the heat map with relative abundance and p-values detailed in the accompanying table produced using the data repository from Hahn et al. (2021).