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. 2022 Oct 19;17(10):e0276376. doi: 10.1371/journal.pone.0276376

Fig 2. The Albino color morph is associated with three haplotypes of TYR.

Fig 2

(A) TYR haplotype frequencies among Albinos and Non-Albinos. (B) Alignment of TYR protein sequences surrounding the missense variants D394G and P384L. (C) TYR genotypes and breeder designations of animals used in the association study. +, any TYR haplotype found exclusively among Non-Albinos. (D) PCR amplification of a genomic fragment containing the variable number tandem repeat (VNTR) shown in E. Non-Albinos are examples of Non-Albinos homozygous for the longer allele of the VNTR. (E) Schematic of the three TYR haplotypes found in Albinos. The TYRAlbino haplotype contains no coding variants and no splice-site variants compared to wildtype. (A, E) Hash mark, discontinuity in the Burmese python reference genome.