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. 2022 Oct 4;13:1020902. doi: 10.3389/fimmu.2022.1020902

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Copyright © 2022 Xiao, Lian, Zhong, Krishnachaitanya, Cong, Dashwood, Savidge, Powell, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential mRNA expression of junction proteins in the colons of wild type and Mmp7 ^-/- mice treated with 3% DSS. Colitis was induced with 3% DSS in drinking water in both C57BL/6 and Mmp7 ^-/- mice for 7 days as shown in Figure 4 . RT-qPCR was performed to determine mRNA levels of Ctnnb1 (A), Cdh1 (B), Cldn1 (C), Cldn7 (D), Cldn13 (E), Cldn15 (F), Ocln (G), Tjp1 (H), Cldn8 (I), Muc2 (J), Muc3 (K), and Muc4 (L). n=4 or 5. *p<0.05 vs wild type control. **p<0.05 vs wild type DSS.