Table 1.
Characteristics of participants who reported ever taking a statin, overall, and by statin discontinuation status.
| Characteristics | Statin discontinuation |
p-value | ||
|---|---|---|---|---|
| Overall (n=7,216) |
Yes (n=1,081) |
No (n=6,135) |
||
|
| ||||
| Age (years) | ||||
| < 65 | 997 (14%) | 188 (17%) | 809 (13%) | <0.001 |
| 65 – 74 | 3,442 (48%) | 519 (48%) | 2,923 (48%) | |
| ≥ 75 | 2,777 (39%) | 374 (35%) | 2,403 (39%) | |
| Black | 2,463 (34%) | 355 (33%) | 2,108 (34%) | 0.33 |
| Woman | 3,840 (53%) | 672 (62%) | 3,168 (52%) | <0.001 |
| Residing in Stroke Belt/Buckle | 4,073 (56%) | 621 (58%) | 3,452 (56%) | 0.47 |
| Less than high school education | 491 (7%) | 54 (5%) | 437 (7%) | 0.01 |
| Current smoker* | 509 (7%) | 63 (6%) | 446 (7%) | 0.09 |
| High perceived stress* | 1,968 (28%) | 296 (27%) | 1,690 (28%) | 0.88 |
| Depressive symptoms* | 763 (11%) | 113 (11%) | 650 (11%) | 0.89 |
| SF-12 physical component score* | ||||
| < 40 | 2,093 (31%) | 357 (35%) | 1,736 (30%) | 0.01 |
| 40–50 | 1,894 (28%) | 266 (26%) | 1,628 (28%) | |
| > 50 | 2,836 (41%) | 409 (39%) | 2,427 (42%) | |
| SF-12 mental component score* | ||||
| < 50 | 1,060 (15%) | 167 (16%) | 893 (15%) | 0.61 |
| 50–60 | 4.078 (60%) | 600 (58%) | 3,478 (60%) | |
| > 60 | 1,685 (25%) | 265 (26%) | 1,420 (25%) | |
| Low medication adherence* | 2,135 (32%) | 346 (35%) | 1,789 (31%) | 0.04 |
| High blood pressure** | 1,017 (14%) | 165 (15%) | 852 (14%) | 0.23 |
| Antihypertensive medication use* | 3,874 (54%) | 510 (47%) | 3,364 (55%) | <0.001 |
| Diabetes mellitus* | 2,165 (31%) | 242 (22%) | 1,923 (32%) | <0.001 |
| History of CVD* | 2,214 (32%) | 261 (25%) | 1,953 (33%) | <0.001 |
| LDL-C (mg/dL)* | ||||
| < 100 | 4,267 (62%) | 278 (27%) | 3,989 (69%) | <0.001 |
| 100 – 129 | 1,491 (22%) | 306 (30%) | 1,185 (20%) | |
| ≥ 130 | 1,076 (16%) | 432 (43%) | 644 (11%) | |
Abbreviations –CVD, cardiovascular disease; LDL-C, low-density lipoprotein-cholesterol; SF-12, 12-item short form survey.
*
missing data for some participants
**
High blood pressure defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg.