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. 2022 Oct 19;8(42):eadd6155. doi: 10.1126/sciadv.add6155

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Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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Fig. 4. — (A) The distribution of participants in the reviewed aging metabolomics studies by country is shown. Most studies have been located in North America, Europe, or East Asia, leaving a substantial gap in our understanding of aging across the world. (B) The regional breakdown of aging metabolomics human population studies by study count and (C) participant count is shown. In both cases, Europe has been represented to a greater extent than other regions. The category “Multiple” includes studies that had cohorts from more than one of the regions listed. Transparent regions were not represented among the human aging metabolomics studies reviewed here.