Table 2.
Sensitivity, specificity, and predictive values of sTfR and standard parameters of iron status alone and in combination for the diagnosis of IDA or ACD/IDA (N = 42) in the whole sample (N = 116).
| Sensitivity % | Specificity % | PPV % | NPV % | |
|---|---|---|---|---|
| RBCI | 23.8 | 95.9 | 76.6 | 69.1 |
| Ferritin | 54.8 | 86.5 | 69.5 | 77.0 |
| Ferritin/RBCI | 66.7 | 86.5 | 73.7 | 88.2 |
| Ferritin/TSAT/RBCI | 66.7 | 91.9 | 82.4 | 83.1 |
| Ferritin/TSAT/CRP/RBCI | 66.7 | 93.2 | 84.3 | 83.4 |
| Ferritin/TSAT/CRP/sTfR/RBCI | 54.8 | 95.9 | 89.9 | 82.6 |
| sTfR | 80.9 | 93.2 | 86.7 | 89.6 |
RBCI: red blood cell indices; IDA: iron deficiency anemia; ACD: anemia of chronic disease; ACD/IDA: anemia of chronic disease with concomitant true iron deficiency; TSAT: transferrin saturation; sTfR: soluble transferrin receptor.