Table 3.
Sensitivity, specificity, and predictive values of sTfR and standard parameters of iron status alone and in combination for the diagnosis of IDA or ACD/IDA (N = 21) in patients with CRP ≤ median = 24.1 mg/l (N = 58).
| Sensitivity % | Specificity % | PPV % | NPV % | |
|---|---|---|---|---|
| RBCI | 19.0 | 100 | 100 | 68.7 |
| Ferritin | 76.2 | 78.4 | 66.6 | 85.3 |
| Ferritin/RBCI | 76.2 | 78.4 | 66.6 | 85.3 |
| Ferritin/TSAT/RBCI | 85.7 | 86.5 | 78.8 | 91.6 |
| Ferritin/TSAT/CRP/RBCI | 76.2 | 100 | 100 | 88.1 |
| Ferritin/TSAT/CRP/sTfR/RBCI | 57.1 | 100 | 100 | 80.5 |
| sTfR | 66.7 | 97.3 | 93.3 | 83.9 |
RBCI: red blood cell indices; IDA: iron deficiency anemia; ACD: anemia of chronic disease; ACD/IDA: anemia of chronic disease with concomitant true iron deficiency; TSAT: transferrin saturation; sTfR: soluble transferrin receptor.