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. 2021 Oct 12;24(5):700–709. doi: 10.1007/s11307-021-01655-4

Fig. 3.

Fig. 3.

In vivo microPET imaging of tMCAO mouse brain using [18F]RoSMA-18-d6. a,b Chemical structures of blocker GW405833 and [18F]RoSMA-18-d6; c representative PET images of horizontal mouse brain sections at different time frames after intravenous injection of [18F]RoSMA-18-d6; SUV: 0–0.5; d,e ratios of [18F]RoSMA-18-d6 uptake under baseline and blockade conditions in cortex and striatum. Significantly higher [18F]RoSMA-18-d6 standard uptake value ratio (SUVR) was observed in the ischemic ipsilateral striatum under baseline conditions, but not in the ipsilateral cortex. Midbrain was used as reference brain region for SUVR calculation. *p < 0.05.