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. 2022 Oct 19;7:60. doi: 10.1038/s41536-022-00256-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 10 — a Tibial length change for the control limbs (dashed) and treatment limbs (solid bars) at 5-, 8-, and 12-weeks post treatment using Formulation A, B, or C. A significant difference was observed between Formulation A and C at 12-weeks post treatment in the treatment limb. *Denotes significant difference in tibial length change of treatment limbs (*p < 0.05; two-way ANOVA, Tukey’s HSD post hoc). b Tibial angle of control limbs (dashed) was similar, as were the tibial angles of the treatment limbs (solid bars) across groups at both 5-, 8-, and 12-weeks post treatment. c No bone metrics measured by microCT were different across scaffold formulations. Data represent mean ± standard deviation (error bars).