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. 2022 Oct 19;13:6203. doi: 10.1038/s41467-022-33968-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Schematic representation of the experiment examining effects of a combination of MWA and CAR T cell administration (n = 5 mice per group). b/c Tumour volume of mice subcutaneously injected with HCC827-ER3 or A549 cells. d, e Mean tumour weight in each group at the end point. f Detection of HLA-A expression in harvested lung tissues from each group. Representative images are shown (n = 5 per group). Positive staining for HLA-A was observed in lung tissues from mock, CD19 and/or MWA groups. Blue arrow indicated metastatic nodules. g Counted metastasis in lungs of each group. h The weight of lungs from each group. i Histopathological analysis of murine organ tissues. Different tissues were harvested, formalin-fixed, paraffin-embedded, and stained using haematoxylin and eosin (HE) staining. Representative staining image fields (magnification ×400) are shown (n = 5 per group). Scale bars represent 100 μm (f) or 50 μm (i). Data are presented as mean ± SD (b‒e, g, h) and analysed by two-way ANOVA (b, c) or one-way ANOVA (d, e, g, h) with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001. Source data and exact p values are provided as a Source Data file.