Fig. 1. A. fumigatus produce GAG in vivo and the multiple roles of GAG in pathogenesis.

a Immunohistochemistry of pulmonary tissue from an immunocompromised mouse infected with A. fumigatus and stained with an anti-galactosaminogalactan antibody. Brown indicates accumulation of galactosaminogalactan-containing biofilm matrix surrounding hyphae growing within pulmonary tissues. b Both cell wall-bound GAG and secreted GAG play multiple roles in Aspergillus pathogenesis. Scale bar: 150 μm.