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. 2022 Oct 19;12:17502. doi: 10.1038/s41598-022-22495-4

Table 2.

Univariable and multivariable logistic regression analysis of variables potentially associated with sPTB in the subsequent pregnancy (n = 1643).

Spontaneous PTB in the subsequent pregnancy
n/N (%) cOR 95%CI aOR 95%CI
Index pregnancy Maternal age ≥ 35 years 13/305 (4.3) 1.5 (0.8–2.8) 1.4 (0.7–2.7)
Maternal age < 20 years 2/29 (6.9) 2.3 (0.5–10.0) 1.6 (0.3–9.2)
Pre-pregnancy BMI < 18.5 kg/m2 16/321 (5.0) 1.9* (1.0–3.4) 1.7 (0.9–3.3)
Nulliparity 38/1313 (2.9) 0.7 (0.4–1.3) 0.7 (0.4–1.4)
Spontaneous PTB 16/66 (24.2) 13.7* (7.1–26.3) 12.7* (6.5–24.8)
Inter-pregnancy Pregnancy interval, years 1.1 (0.9–1.5) 1.1 (0.8–1.5)
Anuual BMI change, kg/m2/year 0.7* (0.5–0.9) 0.6* (0.5–0.9)

n/N: The number of sPTB events in the subsequent pregnancy/the number of patients for each variables; cOR, clude odds ratio; aOR, adjusted OR; CI, confidence interval; BMI, body mass index; PTB, preterm birth.

*Statistically significant.