Table 3.
Univariable and multivariable logistic regression analysis of variables potentially associated with sPTB recurrence (n = 66).
| sPTB recurrence | Non-recurrence | p-value | sPTB recurrence | |||||
|---|---|---|---|---|---|---|---|---|
| cOR | 95%CI | aOR | 95%CI | |||||
| n = 16 | n = 50 | |||||||
| Index-pregnancy | Maternal age ≥ 35 years | 5 (31.3) | 11 (22.0) | 0.509 | 3.3 | (0.2–55.4) | 1.7 | (0.3–8.3) |
| Maternal age < 20 years | 1 (6.3) | 1 (2.0) | 0.429 | 1.6 | (0.5–5.6) | 2.1 | (0.1–41.1) | |
| Pre-pregnancy BMI < 18.5 kg/m2 | 7 (43.8) | 13 (26.0) | 0.217 | 2.2 | (0.7–7.2) | 1.9 | (0.5–8.1) | |
| Inter-pregnancy | Pregnancy interval, years | 2.8 ± 1.5 | 2.1 ± 0.7 | 0.060 | 2.3* | (1.1–4.6) | 2.2 | (1.0–4.8) |
| Anuual BMI change, kg/m2/year | − 0.15 ± 0.81 | 0.34 ± 0.91 | 0.056 | 0.5 | (0.3–1.1) | 0.4* | (0.2–1.0) | |
| Subsequent-pregnancy | Gestational weight gain, kg | 8.1 ± 3.5 | 9.6 ± 3.3 | 0.131 | 0.9 | (0.7–1.1) | 0.9 | (0.7–1.1) |
cOR, clude odds ratio; aOR, adjusted OR; CI, confidence interval; BMI, body mass index; sPTB, spontaneous preterm birth.
*Statistically significant.