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. 2022 Apr 26;35(5):1362–1372. doi: 10.1007/s10278-022-00639-2

Table 2.

Univariate and multivariate analysis of factors

Characteristic Univariate analysis Multivariate analysis
All Clinical model Combined model
OR 95% CI p OR 95% CI p OR 95% CI p
Age (≤ 45, > 45) 0.978 0.972–0.985  < 0.01
Sex 0.565 0.349–0.914 0.02 3.382 1.521–7.520 0.003 3.253 1.374–7.700 0.007
Diameter size (> 1.5 cm, < 1.5 cm) 0.625 0.204–1.910 0.41
Interior structure 0.557 0. 47–0.66  < 0.01 0.265 0.077–0.908 0.035 0.236 0.063–0.884 0.032
Echogenicity 0.549 0.462–0.652  < 0.01
Shape (aspect ratio < 1, > 1) 0.302 0.219–0.417  < 0.01
Edge 1.858 0.867–3.978 0.111 0.026 0.001–0.569 0.02 0.507 0.019–0.623 0.001
Focal strong echogenicity 0.907 0.724–1.136 0.395
WBC (× 109/L) 0.850 0.810–0.892  < 0.01
NEUT# (× 109/L) 0.776 0.716–0.841  < 0.01
LYM (× 109/L) 0.605 0.520–0.703  < 0.01
HB (g/L) 0.992 0.989–0.994  < 0.01
RBC (× 1012/L) 0.781 0.729–0.836  < 0.01
PLT (× 109/L) 0.996 0.994–0.997  < 0.01 1.01 1.003–1.017 0.007 1.01 1.004–1.017 0.002
ALT (U/L) 0.951 0.935–0.966  < 0.01
AST (U/L) 0.951 0.937–0.966  < 0.01
ALB (g/L) 0.974 0.967–0.981  < 0.01
BUN (mmol/L) 0.819 0.771–0.870  < 0.01
CREA (μmol/L) 0.982 0.977–0.987  < 0.01 1.057 1.024–1.091 0.001 1.067 1.034–1.102 0
Radiomics score 1.114 1.083–1.145  < 0.01 1.921 1.425–2.588 0

Variables were compared by using the binary logistic regression

WBC, white blood cell; NEUT, neutrophil; LYM, lymphocyte; HB, hemoglobin; RBC, red blood cell count; PLT, platelets; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; BUN, blood urea nitrogen; CREA, creatinine