Table 3.

Multivariate logistic regression of rapid EGFR decline between study groups according the changes of MetS components

	Model 1		Model 2
	Adjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value
Recovered components in baseline MetS groups (chronic MetS components as reference)
Central obesity	0.29 (0.15 to 0.59)	0.01	0.31 (0.15 to 0.65)	<0.01
Elevated blood pressure	0.80 (0.50 to 1.26)	0.33	0.79 (0.49 to 1.27)	0.33
Elevated SBP	0.89 (0.61 to 1.31)	0.56	0.88 (0.59 to 1.30)	0.51
Elevated DBP	0.75 (0.46 to 1.23)	0.26	0.68 (0.41 to 1.15)	0.15
Dyslipidaemia	1.09 (0.82 to 1.44)	0.57	1.05 (0.78 to 1.40)	0.77
Elevated TG	1.22 (0.87 to 1.72)	0.26	1.14 (0.79 to 1.36)	0.50
Decreased HDL	0.84 (0.59 to 1.12)	0.32	0.85 (0.59 to 1.22)	0.38
Elevated blood glucose	1.08 (0.87 to 1.34)	0.49	1.08 (0.86 to 1.36)	0.52
Elevated fasting glucose	1.14 (0.91 to 1.43)	0.25	1.13 (0.89 to 1.43)	0.32
Developed components in baseline non-MetS groups (free MetS components as reference)
Central obesity	1.21 (0.92 to 1.59)	0.16	1.32 (0.97 to 1.77)	0.74
Elevated blood pressure	0.84 (0.63 to 1.13)	0.26	0.87 (0.64 to 1.18)	0.37
Elevated SBP	0.88 (0.66 to 1.17)	0.37	0.92 (0.68 to 1.23)	0.56
Elevated DBP	0.88 (0.62 to 1.24)	0.46	0.91 (0.63 to 1.30)	0.59
Dyslipidaemia	0.92 (0.69 to 1.22)	0.54	0.96 (0.72 to 1.30)	0.81
Elevated TG	0.93 (0.70 to 1.25)	0.64	1.02 (0.75 to 1.37)	0.91
Decreased HDL	1.02 (0.65 to 1.59)	0.95	0.97 (0.61 to 1.55)	0.91
Elevated blood glucose	1.07 (0.76 to 1.50)	0.71	1.07 (0.75 to 1.52)	0.71
Elevated fasting glucose	1.06 (0.74 to 1.51)	0.76	1.09 (0.76 to 1.57)	0.64

Model 1: additional adjusted for age and sex.

Model 2: additional adjusted for age, sex, serum creatinine, eGFR classification, grip strength classification, haemoglobin, MetS score and body mass index.

Each MetS component runs in their own model to predict rapid eGFR decline.

DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high density lipoprotein; MetS, metabolic syndrome; SBP, systolic blood pressure; TG, triglyceride.