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. 2022 Oct 19;4(2):e000344. doi: 10.1136/bmjno-2022-000344

Table 3.

Associations between cortisol and change in cognition over time

Memory (n=49) Processing speed (n=45)
b 95% CI p b 95% CI p
Awakening cortisol (t1) 0.02 −0.31 to 0.34 0.918 −0.05 −0.39 to 0.30 0.792
Bedtime cortisol (t6) −0.03 −0.21 to 0.14 0.693 −0.02 −0.20 to 0.15 0.795
Cortisol awakening response −0.02 −0.18 to 0.15 0.840 0.03 −0.14 to 0.19 0.760
Daily cortisol output −0.09 −0.36 to 0.19 0.528 −0.02 −0.30 to 0.26 0.862
Cortisol AM/PM ratio (t1/t6) 0.09 −0.17 to 0.34 0.510 −0.02 −0.28 to 0.24 0.895

Results based on linear regressions. All analysis adjusted for age, sex and education. *p<0.05, **p<0.01; ***p<0.001.