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. 2022 Sep 12;43(16):5017–5031. doi: 10.1002/hbm.26066

FIGURE 3.

FIGURE 3

A brain age vector of a prodromal PD patient (aged 62) derived from SHAP feature attribution. The base value (59.52 years) shows the mean chronological age in the training set. Each value (Shapley value) in the brain age vector represents the feature contribution to the estimated brain age (68.03 years). The red features with positive Shapley values contribute to the increase of the brain age estimation from the base value, whereas the blue features with negative Shapley values contribute to the decrease. The arrow lengths indicate the absolute Shapley values, and the corresponding input feature values are explained below the arrows. The sum of the base value and all Shapley values in the brain age vector equals the estimated brain age (68.03 years)