Table 2.
Multivariable analysis for the disease-free survival model based on the Akaike information criterion in the patients with lung cancer
| Variable | Disease-free survival model | |
|---|---|---|
| HR (95% CI) | p-value | |
| Age (yr) | 1.03 (1.01–1.05) | 0.001 |
| Former or current smoker | 1.68 (1.22–2.32) | 0.001 |
| History of malignancy other than lung cancer | 1.44 (1.00–2.06) | 0.049 |
| Pneumonectomy (reference: lobectomy) | 2.09 (1.41–3.11) | < 0.001 |
| TNM stage (reference: 1A) | ||
| 1B | 1.62 (0.96–2.71) | 0.070 |
| 2A | 3.17 (1.66–6.05) | < 0.001 |
| 2B | 3.94 (2.36–6.59) | < 0.001 |
| 3A | 7.38 (4.29–12.70) | < 0.001 |
| 3B or 3C | 15.41 (8.08–29.4) | < 0.001 |
| Interaction of cancer type and treatment (reference: SqCC and operation only) | ||
| SqCC and adjuvant therapy | 0.26 (0.16–0.44) | < 0.001 |
| ADC and operation only | 0.39 (0.24–0.65) | < 0.001 |
| ADC and adjuvant therapy | 0.72 (0.45–1.15) | 0.170 |
ADC, adenocarcinoma; Adjuvant therapy, adjuvant chemo- or radiation therapy; CI, confidence interval; HR, hazard ratio; SqCC, squamous cell carcinoma.