Table 2.

Germline mutant patient characteristics

Patient ID	Age (yr)	Stage	Histology	Gene	AA change	Variant type
CC_006	35	IIA	ADC	MPL	W398X	Nonsense variant
CC_007	44	IIA	SCC	MMP1	A330LfsX45	Frame shift variant
CC_015	41	IB	SCC	PMS1	K894RfsX17	Frame shift variant
CC_019	36	IB	SCC	AXIN2	R714W	Missense variant
CC_028	60	IB	SCC	BRCA1	c.4358-2A>G	Splice variant
CC_028	60	IB	SCC	BRIP1	S618*	Nonsense variant
CC_034	66	IB	SCC	EPCAM	L78R	Missense variant
CC_036	59	IIA	SCC	PALB2	S537L	Missense variant
CC_039	50	IB	SCC	MUTYH	Y453C	Missense variant
CC_039	50	IB	SCC	TP53	A86V	Missense variant
CC_056	43	IIA	SCC	BRCA2	S2414*	Nonsense variant
CC_072	38	IB	ADC	FANCE	S157Kfs*21	Frame shift variant
CC_079	41	IIA	SCC	BRCA1	S451Lfs*20	Frame shift variant
CC_081	44	IB	ADC	MLH1	S295G	Missense variant
CC_111	42	IB	SCC	FANCM	L923Cfs*3	Frame shift variant

ADC, adenocarcinoma; SCC, squamous cell carcinoma.