Table 2.

Univariate and multivariate cox regression analyses of prognostic factors in 416 cases of low-grade glioma (LGG).

Parameter	Univariate analysis		Multivariate analysis
	HR (95% CI)	P-Value	HR (95% CI)	P-Value
Age (continuous, years)	1.06 (1.04-1.07)	<0.001	1.06 (1.01-1.10)	0.011
Gender (ref. Female)	1.11 (0.78-1.58)	0.574	2.01 (0.71-5.80)	0.184
Grade (ref. WHO II)	3.37 (2.28-4.98)	<0.001	0.85 (0.25-2.9)	0.795
IDH_mutation (ref. Wildtype)	0.18 (0.07-0.48)	<0.001	0.40 (0.12-1.40)	0.142
FNDC3B (continuous)	1.64 (1.50-1.80)	<0.001	1.72 (1.07-2.80)	0.026

Bold values means p<0.05.