Table 4.
Immune cell types | Gene markers | LGG | GBM | ||
---|---|---|---|---|---|
Cor | P | Cor | P | ||
B cells | CD2 | 0.42 | *** | 0.3 | *** |
CD74 | 0.48 | *** | 0.31 | *** | |
CD27 | 0.24 | *** | 0.3 | *** | |
Plasma cells | SPAG4 | 0.3 | *** | 0.29 | *** |
PDK1 | 0.37 | *** | 0.2 | ** | |
MAST1 | -0.31 | *** | −0.27 | *** | |
MANEA | 0.64 | *** | 0.2 | * | |
T cells | CD2 | 0.42 | *** | 0.3 | *** |
CD3E | 0.38 | *** | 0.32 | *** | |
CD3D | 0.37 | *** | 0.21 | ** | |
CD4+ T cells | CD4 | 0.47 | *** | 0.42 | *** |
Tfh | BCL6 | 0.16 | *** | 0.28 | *** |
CD84 | 0.47 | *** | 0.32 | *** | |
IL6R | 0.46 | *** | 0.4 | *** | |
IL21 | 0.22 | *** | 0.19 | * | |
M1 Macrophage | CD80 | 0.36 | *** | 0.28 | *** |
IRF5 | 0.41 | *** | 0.26 | *** | |
IL6 | 0.19 | *** | 0.42 | *** | |
CD64 | 0.24 | *** | 0.21 | ** | |
M2 Macrophage | CD163 | 0.4 | *** | 0.43 | *** |
CD206 | 0.12 | ** | 0.57 | *** | |
VSIG4 | 0.34 | *** | 0.3 | *** | |
MS4A4A | 0.35 | *** | 0.36 | *** | |
Dendritic cell | HLA-DPB1 | 0.47 | *** | 0.3 | *** |
HLA-DQB1 | 0.36 | *** | 0.27 | *** | |
HLA-DRA | 0.52 | *** | 0.24 | ** | |
HLA-DPA1 | 0.47 | *** | 0.27 | *** | |
CD8A | 0.43 | *** | 0.25 | ** | |
CD141 | 0.35 | *** | 0.6 | *** | |
NRP1 | 0.63 | *** | 0.81 | *** | |
Neutrophils | CCR1 | 0.45 | *** | 0.41 | *** |
CD11B | 0.46 | *** | 0.56 | *** | |
CCR7 | 0.25 | *** | 0.3 | *** | |
SLC1A5 | 0.42 | *** | 0.43 | *** | |
CXCR2 | 0.38 | *** | 0.22 | ** |
*P < 0.05; **P < 0.01; ***P < 0.001.