Table 4.

Changes in the composition of BM cell populations in serial hemodilution experiments. Distribution of parameters used in the ALLgorithMM to define hemodilution of BM samples, within 4 different scenarios simulated for each patient: nonHD (sample as it is), MHD (sample diluted with PB to obtain an MHD sample), MHDlow (sample diluted with PB to obtain an MHD sample nearly HD), and HD (full hemodiluted sample). In parentheses are represented in silico-derived values, as expected by applying serial dilutions of samples to simulate the 4 different cases.

Type of Cells	1pt1 nonHD	pt1 MHD	pt1 MHDlow	pt1 HD	pt2 nonHD	pt2 MHD	pt2 MHDlow	pt2 HD
IG/N ratio	2.79	0.89 (0.8)	0.66 (0.6)	0.43 (0.4)	1.61	0.76 (0.8)	0.62 (0.6)	0.41 (0.4)
Mast cells	0.003%	0.001% (0.0008%)	0.001% (0.0006%)	0.001% (0.0004%)	0.039%	0.023% (0.02%)	0.02% (0.015%)	0.012% (0.01%)
Erythroblasts	9.5%	6.2% (5.72%)	4.1% (4.04%)	3.2% (3.36%)	9.2%	4.1% (4.5%)	3.8% (3.42%)	2.2% (2.28%)

¹pt: patient.