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. 2022 Oct 6;9:1024790. doi: 10.3389/fcvm.2022.1024790

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Copyright © 2022 Toor, Aldous, Parray, Akhtar, Al-Sarraj, Abdelalim, Arredouani, El-Agnaf, Thornalley, Pananchikkal, Pir, Kuni, Shuaib, Alajez and Albagha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional enrichment analysis of the proteins encoded by the gene targets of dysregulated miRNAs in SWDM versus SWoDM patients. (A) The protein–protein interaction (PPI) network generated for the 47 gene targets of the identified miRNA panel is shown. Network nodes represent proteins, while edges depict protein–protein associations. The key network statistics are also presented. (B) The top functional enrichment annotations from Gene Ontology (GO), biological process (BP)/molecular function (MF), and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways are listed.