TABLE 3.

ROI-to-ROI time by intervention interaction in PPI connectivity: Exploratory results.

	Seed name			Target name			t-value	P uncorrected
	Hemisphere	Net	Node	Hemisphere	Net	Node
Increased PPI	Right	VAN	Med	Right	ECN	PFCmp	2.64	0.013402
	Left	ECN	PcunCing	Right	ECN	PFCmp	2.55	0.016381
	Right	ECN	PFCmp	Right	VAN	Med	2.48	0.019412
	Left	ECN	PcunCing	Right	VAN	Med	2.42	0.022014
	Right	VAN	Med	Right	ECN	PcunCing	2.39	0.023892
	Right	ECN	PcunCing	Left	VAN	TempOcc	2.3	0.029055
	Right	ECN	PcunCing	Right	VAN	Med	2.22	0.034496
	Left	VAN	ParOper	Right	ECN	PcunCing	2.12	0.043024
Decreased PPI	Right	VAN	PFC	Left	VAN	FrOperIns	–2.46	0.020392
	Left	DMN	TempPar	Left	ECN	PcunCing	–2.45	0.020622
	Left	DMN	PcunPCC	Left	DMN	PFC	–2.41	0.023009
	Left	DMN	TempPar	Right	DMN	PFC	–2.37	0.024863
	Left	DMN	PFC	Left	DMN	PcunPCC	–2.28	0.030705
	Left	ECN	PcunCing	Left	ECN	TempPar	–2.07	0.04799

Main nodes in VAN, ECN, and DMN (a total of 24 ROIs) were considered for an ROI-to-ROI gPPI analysis. Significant time by intervention with P uncorrected < 0.05 are reported. Positive t-values represent enhanced PPI connectivity changes between seed and target in active compared to sham, while negative t-values stand for decreased PPI connectivity changes between seed and target in active compared to sham. ECN, frontoparietal network; DMN, default mode network; VAN, ventral attention network; FrOperIns, frontal-operculum-insula; Med, medial; ParOper, parietal-operculum; PFC, Prefrontal cortex; TempOcc, tempro-occipital-parietal; TempPar, tempro-parietal; PcunCing, precuneus cingulate; PcunPCC, precuneus posterior cingulate cortex; Net, large-scale network (ECN, DMN, or VAN); increased PPI: t-value > 0 (an enhanced PPI connectivity between seed and target in active the tDCS, while it decreased in the sham). Decreased PPI: t-value < 0 (a decreased PPI connectivity between seed and target in the active tDCS, while it increased in sham).