Table 1.
Comparison of the antimicrobial susceptibility rates of Escherichia coli isolates in clinical features.
| Antibiotic | %S | MIC50 | MIC90 | Gender (%) | Age (%) | Primary infection(%) | Bloodstream infection(%) | ICU admission(%) | Clinical outcome(%) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Female N = 442 |
Male N = 454 |
p-Value | ≤ 65 N = 506 | > 65 N = 385 | p-Value | CO N = 497 | HA N = 348 | p-Value | CO N = 504 | HA N = 390 | p-Value | Yes N = 127 | No N = 729 | p-Value | Death N = 36 |
Others N = 834 |
p-Value | ||||
| Polymyxin B | 99.0 | 0.25 | 0.5 | 98.6 | 99.3 | 0.335 | 98.8 | 99.2 | 0.739 | 99.4 | 98.6 | 0.285 | 99.2 | 98.7 | 0.698 | 98.8 | 99.0 | 1.000 | 97.2 | 99.0 | 0.318 |
| Colistin | 98.5 | 0.25 | 0.5 | 98.2 | 98.9 | 0.375 | 98.0 | 99.2 | 0.140 | 98.8 | 98.3 | 0.742 | 98.8 | 98.2 | 0.454 | 98.2 | 98.6 | 0.956 | 97.2 | 98.7 | 0.400 |
| Ceftazidime/avibactam | 99.8 | 0.064 | 0.064 | 99.8 | 99.8 | 1.000 | 99.8 | 99.7 | 1.000 | 99.8 | 99.7 | 1.000 | 100.0 | 99.5 | 0.190 | 100.0 | 99.7 | 1.000 | 100.0 | 99.8 | 1.000 |
| Aztreonam/Avibactam | 99.7 | 0.064 | 0.064 | 99.5 | 99.8 | 0.620 | 99.4 | 100.0 | 0.263 | 99.8 | 99.4 | 0.572 | 100.0 | 99.2 | 0.083 | 98.8 | 99.9 | 0.091 | 100.0 | 99.6 | 1.000 |
| Amikacin | 98.0 | 2 | 4 | 98.0 | 98.0 | 0.954 | 97.6 | 98.4 | 0.393 | 98.4 | 98.0 | 0.663 | 98.0 | 97.9 | 0.943 | 96.4 | 98.4 | 0.190 | 100.0 | 98.1 | 1.000 |
| Meropenem | 96.9 | 0.064 | 0.064 | 97.1 | 96.7 | 0.755 | 96.4 | 97.7 | 0.293 | 97.0 | 96.8 | 0.906 | 97.4 | 96.2 | 0.281 | 97.0 | 96.8 | 0.914 | 100.0 | 96.9 | 0.565 |
| Imipenem | 96.5 | 0.25 | 0.5 | 96.6 | 96.5 | 0.915 | 96.4 | 97.1 | 0.560 | 97.0 | 96.0 | 0.430 | 97.4 | 95.4 | 0.099 | 97.0 | 96.4 | 0.715 | 100.0 | 96.5 | 0.507 |
| Piperacillin/Tazobactam | 94.8 | 8 | 8 | 95.7 | 93.8 | 0.210 | 93.9 | 96.1 | 0.136 | 95.2 | 94.3 | 0.554 | 95.6 | 93.6 | 0.174 | 95.8 | 94.5 | 0.498 | 100.0 | 94.6 | 0.295 |
| Ertapenem | 92.7 | 0.064 | 0.25 | 93.9 | 91.6 | 0.192 | 92.1 | 93.8 | 0.338 | 92.8 | 93.1 | 0.847 | 92.9 | 92.6 | 0.867 | 88.0 | 93.8 | 0.009* | 100.0 | 92.4 | 0.166 |
| Cefoxitin | 86.6 | 2 | 16 | 88.0 | 85.2 | 0.224 | 86.2 | 87.5 | 0.551 | 87.7 | 85.6 | 0.375 | 87.9 | 84.9 | 0.188 | 89.2 | 86.0 | 0.271 | 91.7 | 86.2 | 0.492 |
| Cefoperazone/Sulbactam | 85.0 | 8 | 32 | 86.2 | 83.9 | 0.339 | 83.8 | 86.8 | 0.220 | 85.7 | 83.9 | 0.470 | 85.9 | 83.8 | 0.391 | 80.8 | 86.0 | 0.091 | 86.1 | 85.3 | 0.887 |
| Ceftazidime | 69.0 | 1 | 64 | 71.3 | 66.7 | 0.143 | 67.4 | 71.2 | 0.227 | 71.8 | 66.1 | 0.075 | 71.6 | 65.4 | 0.046* | 59.3 | 71.2 | 0.003* | 80.6 | 68.3 | 0.121 |
| Cefepime | 53.5 | 2 | 128 | 54.1 | 52.9 | 0.717 | 52.0 | 55.6 | 0.285 | 55.3 | 52.3 | 0.384 | 55.0 | 51.3 | 0.274 | 44.3 | 55.6 | 0.009* | 58.3 | 53.2 | 0.548 |
| Sitafloxacin | 49.1 | 0.5 | 2 | 49.3 | 48.9 | 0.899 | 46.8 | 52.2 | 0.112 | 50.3 | 49.7 | 0.866 | 48.8 | 49.5 | 0.841 | 45.5 | 49.9 | 0.302 | 38.9 | 49.5 | 0.212 |
| Levofloxacin | 42.6 | 2 | 16 | 45.0 | 40.3 | 0.154 | 40.1 | 45.7 | 0.094 | 43.9 | 44.0 | 0.976 | 42.1 | 43.3 | 0.703 | 41.3 | 42.9 | 0.703 | 36.1 | 42.8 | 0.426 |
| Ceftriaxone | 42.2 | 64 | 256 | 42.8 | 41.6 | 0.732 | 40.3 | 44.9 | 0.167 | 44.1 | 42.2 | 0.599 | 43.8 | 40.0 | 0.248 | 35.3 | 43.8 | 0.047* | 44.4 | 42.0 | 0.768 |
| Trimethoprim/sulfamethoxazole | 34.7 | 8 | 8 | 34.4 | 35.0 | 0.842 | 30.4 | 40.0 | 0.003* | 38.8 | 29.0 | 0.003* | 39.3 | 28.7 | 0.001* | 34.1 | 34.8 | 0.862 | 50.0 | 33.9 | 0.047* |
*
p < 0.05.