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. 2022 Oct 6;13:961817. doi: 10.3389/fphar.2022.961817

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Copyright © 2022 Zhang, Xue, Jing, Tian, Zhang, Li, Lu, Chen, Diao, Chen, Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ionized calcium-binding adapter molecule (Iba-1) expression in the PFC, HIP, SN, and amygdala for all groups (n = 3). (A) The AOD value of each group was compared. Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.005, compared to the control group. (B) Representative photomicrographs of Iba-1 expression in the PFC (×400). (C) Representative photomicrographs of Iba-1 expression in the HIP (×400). (D) Representative photomicrographs of Iba-1 expression in the SN (×400). (E) Representative photomicrographs of Iba-1 expression in the amygdala (×400). The arrows showed the expression of activated microglia.