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. 2022 Oct 6;13:974996. doi: 10.3389/fimmu.2022.974996

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Copyright © 2022 Xu, Xiao, Li, Xin, Song, Zhan, Wang, Zhang, Yuan, Tan and Fang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Origin of GAMs and their role in glioma. GAMs originate from BRM and BMDMs. GAMs regulate glioma tumor growth, invasion, angiogenesis, energy metabolism, and therapy resistance.