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. 2022 Oct 6;10:1011388. doi: 10.3389/fpubh.2022.1011388

Table 2.

Association of clinical co-morbidities with latent tuberculosis-infected South Indian adult population enrolled between 2013 and 2020.

Variable LTBI P-value LTBI P-value
OR (95% Cl) aOR (95% Cl)
Socio-demographic characteristics-sex
Female Reference 0.001 Reference 0.001
Male 1.47 (1.25–1.74) 1.49 (1.26–1.76)
Age, years
18–34 Reference 0.018 Reference 0.043
35–44 1.21 (0.98–1.49) 1.23 (0.99–1.52)
45–54 1.25 (1.01–1.56) 1.24 (0.98–1.57)
≥55 1.46 (1.13–1.89) 1.33 (1.1–1.76)
BMI (kg/m 2 )
Normal (18.5–22.9) Reference 0.243 Reference 0.389
Undernutrition ( ≤ 18.5) 1.07 (0.78–1.48) 1.15 (0.83–1.60)
Overweight (23.0–24.9) 0.86 (0.67–1.09) 0.82 (0.64–1.05)
Obesity (≥25.0) 0.85 (0.70–1.03) 0.84 (0.69–1.03)
HbA1c (%)
NDM ( ≤ 5.7) Reference 0.032 Reference 0.040
PDM (>5.7– < 6.4) 1.11 (1.0–1.35) 1.10 (0.90–1.35)
DM (>6.4) 1.26 (1.13–1.65) 1.19 (1.10–1.58)
HTN (mm Hg)
Systolic pressure ≤ 130 Reference 0.028 Reference 0.043
Systolic pressure >130 1.28 (1.11–1.62) 1.18 (1.0–1.56)

LTB, latent tuberculosis; BMI, body mass index; HbA1c, glycated hemoglobin; NDM, non-diabetes mellitus; PDM, pre-diabetes mellitus; DM, diabetes mellitus; HTN, hypertension; Cl, confidence interval; OR, odds ratio; and aOR, adjusted odds ratio.