Table 7.
Multiple linear regression of relative abundance of 3GalNAc glycoform with age, sex, race, MAP, eGFR, urinary protein, antihypertensive medication use (n = 59; consists of only patients with IgAN)
| Independent variable | Regression coefficient (95% confidence interval) | p value |
|---|---|---|
| Age (years) | −0.016 (−0.059 to 0.028) | 0.469 |
| Male (Ref: female) | −0.059 (−1.004 to 0.885) | 0.900 |
| Greek (Ref: Japanese) | −0.462 (−1.545 to 0.620) | 0.395 |
| MAP (mm Hg) | 0.037 (−0.005 to 0.080) | 0.084 |
| eGFR (ml/min/1.73 m2) | −0.026 (−0.048 to −0.003) | 0.029 |
| Urinary protein (g/gCr) | −0.029 (−0.207 to 0.149) | 0.744 |
| Antihypertensive medication use, yes (Ref: no) | 0.575 (−0.485 to 1.635) | 0.281 |
GalNAc, N-acetylgalactosamine; HR, hinge region; IgAN, IgA nephropathy; HC, healthy control; MAP, mean arterial pressure; eGFR, estimated glomerular filtration rate.