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. 2022 Oct 6;9:960259. doi: 10.3389/fcvm.2022.960259

TABLE 3.

Risk factors for recurrence of atrial fibrillation (AF) by multivariate Cox regression analysis model.

Variable Model 3
Model 4
HR (95% CI) P-value HR (95% CI) P-value
Hypertension 1.22 (0.82∼1.81) 0.336 1.29 (0.86∼1.92) 0.219
Duration of AF (≥3 years) 1.54 (1.08∼2.18) 0.017 1.48 (1.04∼2.11) 0.032
Persistent AF 1.56 (1.10∼2.20) 0.012 1.46 (1.03∼2.07) 0.035
LAD 1.06 (1.03∼1.09) <0.001 1.06 (1.03∼1.09) <0.001
CHA2DS2-VASc score 1.05 (0.95∼1.17) 0.357 1.06 (0.92∼1.22) 0.443
BMI 1.03 (0.97∼1.08) 0.368
Age 1.00 (0.98∼1.03) 0.976
FIB-4, continuous variable 1.24 (1.12∼1.38) <0.001
NFS, continuous variable 1.28 (1.07∼1.52) 0.008

Model 3 included hypertension, duration of AF (≥3 years), persistent AF, LAD, CHA2DS2-VASc score, BMI, and FIB-4; Model 4 included hypertension, duration of AF (≥3 years), persistent AF, LAD, CHA2DS2-VASc score, age, and NFS. The variables in the liver fibrosis score formula were not enrolled in the multivariate Cox analysis model. AF, atrial fibrillation; LAD, left atrial diameter; BMI, body mass index; FIB-4, fibrosis-4; NFS, non-alcoholic fatty liver disease fibrosis score; HR, hazard ratio; CI, confidence interval.