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. Author manuscript; available in PMC: 2022 Oct 20.
Published in final edited form as: Nat Cardiovasc Res. 2022 Jan 12;1(1):85–100. doi: 10.1038/s44161-021-00009-1

Extended Data Fig. 9 |. Mendelian Randomization to determine gene-regulatory network causality.

Extended Data Fig. 9 |

Stack plots showing fraction of tissue-specific GRNs considered causal in MR analysis (Methods). The hypergeom function from the SciPy stats package in Python62 was used to test overlaps with tissue-specific causal networks (blue, Extended Data Table 5) in relation to the total number of GRNs in each STARNET tissue (yellow, FDR < 5% according to Storey and Tibshirani63).