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. 2022 Oct 20;19:36. doi: 10.1186/s12014-022-09373-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Principal component analysis and differential analysis of proteomic data from tumors and NATs from three sampling methods. A Analysis of tumors and NATs in bulk samples. B Analysis of tumors and NATs in coring samples. C Analysis of tumors and NATs in LMD samples, D Volcano plot of differentially expressed proteins in bulk samples, E Volcano plot of differentially expressed proteins in coring samples; F Volcano plot of differentially expressed proteins in LMD samples