Fig. 5.

The variant allele frequencies (VAFs) of KRAS mutations in tumors prepared by bulk, coring, and LMD. A The scatterplot of percent of VAF for KRAS mutations based on the paired bulk and coring WES of 8 PDAC samples. B The scatterplot of VAFs of KRAS mutations based on the paired bulk and LMD of 8 PDAC samples. C The scatterplot of VAFs of KRAS mutations based on the paired cores and LMD of 8 PDAC samples. D The percent of VAF for KRAS mutations in 8 cases of PDAC tumors prepared by bulk, coring, and LMD methods. E The fold changes of VAFs from tumors prepared by coring or LMD comparing to the original VAFs from the bulk tumors