Table 1.

Overlapped metabolites identified for the four different GWAS datasets of anxiety disorders

Description	Anxiety disorders diagnosed by psychiatrists		Unspecified anxiety disorders diagnosed by secondary ICD-10		Anxiety disorders diagnosed by general practitioners		Self-reported anxiety
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
1-arachidonoylglycerophosphocholine	0.975(0.958–0.992)	0.004**					0.993(0.987–0.999)	0.020
1-eicosatrienoylglycerophosphocholine	1.017(1.001–0.033)	0.039*			1.045(1.022–1.069)	0.000***
1-linoleoylglycerophosphoethanolamine	1.040(1.021–1.060)	0.000***			1.054(1.025–1.084)	0.000***
adrenate (224n6)	0.969(0.942–0.997)	0.032*			0.958(0.920–0.997)	0.035*
androsterone sulfate	1.010(1.003–1.016)	0.007**			1.009(1.001–1.017)	0.031*
cholate	1.009(1.002–1.017)	0.011*					1.004(1.001–1.007)	0.005
docosahexaenoate (DHA; 226n3)	0.971(0.947–0.995)	0.019*			0.949(0.906–0.994)	0.025*
epiandrosterone sulfate	1.012(1.001–1.023)	0.029*					0.995(0.992–0.998)	0.003
gamma-glutamylphenylalanine	0.961(0.935–0.987)	0.003**			0.959(0.921–0.999)	0.043*
phenyllactate (PLA)	0.958(0.933–0.984)	0.002**			0.952(0.907–0.998)	0.041*
tryptophan betaine	1.008(1.002–1.015)	0.010*			1.014(1.003–1.025)	0.012*

OR, odds ratio; CI, confidence interval

*p < 0.05

**p < 0.01

***p < 0.001