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. 2022 Oct 6;7(41):36762–36775. doi: 10.1021/acsomega.2c05079

Figure 12.

Figure 12

Two-dimensional (2D) free-energy landscape for the interaction between the FP-L and the POPC bilayer (30% cholesterol), and free energy unit is kJ/mol. dCTM-Surface represents the z distance from the FP C-terminus to the POPC bilayer surface, while dNTM-Surface corresponds to the z distance from the FP N-terminus to the POPC bilayer surface. We labeled the most stable state with I. Some hydrophobic residues of the FP-S is represented by color spheres and the phosphate groups by yellow spheres.