Table 4:
Characteristic firing frequencies (initial and average) at different current injection strengths from conditioning hyperpolarized potentials for randomly sampled (Random) and Y1eGFP SDH neurons. Numbers in brackets indicate number of animals. LCI, MCI and HCI denote Low, Medium, and High strengths of current injection. DSLF stand for delayed short latency firing (N is non-adapting, A is adapting), DLLF for delayed long latency firing, IBF for initial burst firing and TF for tonic firing. 1–5 neurons averaged for each mouse. Values represent mean ± SD.
| Random | Y1eGFP | |||||||
|---|---|---|---|---|---|---|---|---|
| LCIA | MCIB | HCIC | LCID | MCIE | HCIF | |||
| Initial spike frequency (Hz) | DSLF-N | 16±9 (9) | 34±10 (8) | 41±16 (9) | DSLF-A | 18±7 (19) | 30±9 (18) | 36±11 (18) |
| DLLF | 35±30 (5) | 49±31 (5) | 52± 38 (5) | DLLF | 16±4 (13) *(AD) | 27±11 (13) *(BE) | 31±10 (13) **(CF) | |
| IBF | 29±19 (4) | 49±30 (4) | 66±28 (4) | IBF | 78±32 (8) *(AD) | 107±21 (7) **(BE) | 96±35 (8) | |
| TF | 10±1 (2) | 74±15 (2) | 104±17 (2) | TF | 25±18 (2) | 88±54 (2) | 114±54 (2) | |
| Average spike frequency (Hz) | DSLF-N | 14±7 (9) | 33±14 (8) | 39±18 (9) | DSLF-A | 15±7 (17) | 25±6 (16) *(BE) | 31±7 (16) |
| DLLF | 22±23 (5) | 32±12 (5) | 35±19 (5) | DLLF | 13±3 (12) | 25±8 (12) | 29±9 (12) | |
| IBF | 23±13 (5) | 46±22 (5) | 62±20 (5) | IBF | 56±26 (8) *(AD) | 61±24 (7) | 63±28 (8) | |
| TF | 9±1 (2) | 61±7 (2) | 82±9 (2) | TF | 28±27 (2) | 75±47 (2) | 88±45 (2) | |
*
p<0.05,
**
p<0.01 or
***
p<0.001, Student’s t-test, for respective injecting strengths, Random vs. Y1eGFP.