Table 5:
Characteristic frequency adaptation [initial and average of all ] at different current injection strengths from conditioning hyperpolarized potentials for randomly sampled (Random) and Y1eGFP SDH neurons. Number in brackets indicates number of animals. LCI, MCI and HCI denote Low, Medium and High strengths of current Injection. DSLF stand for delayed short latency firing (N is non-adapting, A is adapting), DLLF for delayed long latency firing, IBF for initial burst firing and TF for tonic firing. 1–5 neurons averaged for each mouse. Values represent mean ± SD.
| Random | Y1eGFP | |||||||
|---|---|---|---|---|---|---|---|---|
| LCIA | MCIB | HCIC | LCID | MCIE | HCIF | |||
| Initial frequency adaptation | DSLF-N | −0.13±0.13 (9) | −0.01±0.19 (8) | −0.04±0.18 (9) | DSLF-A | −0.21±0.14 (18) | −0.14±0.11 (17) *(BE) | −0.10±0.09 (18) |
| DLLF | −0.14±0.61 (5) | 0.07±0.23 (5) | −0.09±0.09 (5) | DLLF | −0.15±0.16 (12) | 0.11±0.20 (12) | 0.09±0.16 (12) *(CF) | |
| IBF | 0.08±0.35 (4) | −0.16±0.27 (4) | −0.18±0.30 (4) | IBF | −0.47±0.09 (7) **(AD) | −0.32±0.10 (7) | −0.25±0.35 (7) | |
| TF | −0.09±0.01 (2) | 0.01±0.01 (2) | −0.04±0.02 (2) | TF | 0.33±0.12 (2) *(AD) | 0.04±0.13 (2) | −0.01±0.05 (2) | |
| average frequency adaptation | DSLF-N | −0.05±0.13 (9) | −0.00±0.05 (8) | −0.03±0.04 (9) | DSLF-A | −0.11±0.03 (15) | −0.07±0.05 (15) **(BE) | −0.08±0.04 (17) **(CF) |
| DLLF | −0.04±0.13 (5) | −0.04±0.04 (5) | −0.05±0.03 (5) | DLLF | −0.09±0.08 (12) | −0.03±0.03 (12) | −0.04±0.06 (12) | |
| IBF | −0.01±0.11 (4) | 0.00±0.05 (4) | −0.02±0.03 (4) | IBF | −0.2±0.16(7) *(AD) | −0.19±0.13 (7) *(BE) | −0.12±0.08 (7) *(CF) | |
| TF | −0.42±0.43 (2) | −0.00±0.00 (2) | −0.00±0.00 (2) | TF | −0.15±0.17 (2) | −0.00±0.00 (2) | −0.01±0.01 (2) | |
*
p<0.05,
**
p<0.01 or
***
p<0.001: Student’s t-test, for respective injecting strengths, randomly sampled vs. Y1eGFP.