Table 7:
Duration (ms) of decay constant (τ) and sustained currents for randomly sampled (Random) and Y1eGFP superficial dorsal horn neurons exhibiting Fast (IAf) and Slow (IAs) A-type currents in the absence of TEA, Cd2+ and TTX. Both decay constants and sustained currents were measured for currents elicited by voltage steps from −80 mV to a sub-threshold range between −55 to −40 mV (in +5 mV steps). τ was obtained by fitting a single exponent to the decay component of the transient outward current. Sustained currents were measured at 250 ms after activation (steady state). Values represent mean ± SD. Numbers in brackets indicates number of neurons from as many animals.
| Mem. pot. (mV) | IAf | IAs | ||||||
|---|---|---|---|---|---|---|---|---|
| Random | Y1eGFP | Random | Y1eGFP | |||||
| τ (8) | Sustained Current (8) | τ (11) | Sustained Current (11) | τ (3) | Sustained Current (3) | τ (10) | Sustained Current (10) | |
| −55 | 32±16 | 22±18 | 26±8 | 16±27 | 146±99 | 43±42 | 242±65 | 15±29 |
| −50 | 36±11 | 30±24 | 29±8 | 18±27 | 205±196 | 64±54 | 243±85 | 29±35 |
| −45 | 35±12 | 41±32 | 29±7 | 22±31 | 144±67 | 87±70 | 238±90 | 52±44 |
| −40 | 38±14 | 49±37 | 27±6 | 27±32 | 123±42 | 114±88 | 204±71 | 78±54 |