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. 2022 Oct 20;3(4):e182. doi: 10.1002/mco2.182

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© 2022 The Authors. MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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DNA methylation correlates inversely with CASZ1 expression and affects the outcome of glioma patients. (A) Distribution of CASZ1 methylation island in promoter region. (B and C) CASZ1 methylation data were obtained from GEO datasets. (D) The effect of CASZ1 gene methylation on prognosis was analyzed by Kaplan–Meier survival curve in 139 glioma patients. (E) The effect of CASZ1 gene methylation level on prognosis of patients was verified by TCGA data. (F and G) Differentially methylation genes negatively correlated with CASZ1 expression level.