Figure 7. Myofibroblast-like CAF plasticity pathway.
Tumor cells secrete osteopontin which induces MSC to myCAF transformation. myCAF phenotype increases cancer stemness through secreted chemokines (the image made by our lab).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.