Figure 3. The identification of serum metabolite markers and construction of diagnostic model for early NAFLD.
(A) The cross-validation curves showed 32 serum metabolites were selected as the optimal markers. (B,D) The POD index was significantly higher in NAFLD than HC groups both in the discovery set (B) and in the validation set (D). (C) The receiver operating characteristic curve in the discovery set. (E) The receiver operating characteristic curve in the validation set; AUC, area under the curve; CV error, cross-validation error; HC, healthy controls; NAFLD, nonalcoholic fatty liver disease patients; POD, probability of disease.