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Spatial memory retention in the first (A) and second (B) probe trials. Between sessions 8 and 9 of the water maze, and after session 10, the platform was removed from the pool during probe trials. Mice spending more time in the part of the pool where the platform was located previously (target quadrant) reflects better performance. XN-treated WT mice spent more time in the target quadrant than WT mice only on a HFD. *p < 0.05. All graphs show the mean ± SEM.
