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. 2022 Oct 3;13:954980. doi: 10.3389/fphar.2022.954980

TABLE 2.

Glucose transporter protein levels (in ng/mg protein) affected by XN in the hippocampus and cortex in the standard exposure experiment.

Female Male
HFD XN P-value HFD XN P-value
Hippocampus Wildtype
Glut 1 4.87 0.25 5.23 0.30 0.83 5.30 0.35 5.36 0.35 0.97
Glut 3 19.89 0.99 20.76 1.09 0.77 20.31 0.82 20.74 0.90 0.89
Glut 4 0.056 0.004 0.097 0.014 0.07 0.061 0.008 0.062 0.007 0.95
E3
Glut 1 4.74 0.72 8.39 1.93 0.07 8.29 1.14 8.26 1.59 0.99
Glut 3 20.41 1.18 22.20 1.65 0.60 24.17 1.08 26.34 2.41 0.52
Glut 4 0.084 0.015 0.080 0.019 0.86 0.159 0.023 0.153 0.024 0.79
E4
Glut 1 10.94 0.67 16.18 2.73 0.007 12.57 1.35 14.89 2.69 0.27
Glut 3 22.98 1.49 31.78 5.13 0.008 27.18 1.80 32.02 5.02 0.18
Glut 4 0.183 0.012 0.222 0.020 0.11 0.199 0.014 0.238 0.038 0.16
Cortex Wildtype
Glut 1 20.50 0.77 20.79 0.85 0.84 18.47 0.76 19.04 0.52 0.70
Glut 3 19.28 1.04 20.96 0.57 0.22 17.85 0.90 19.31 0.90 0.31
Glut 4 0.43 0.01 0.47 0.02 0.41 0.41 0.01 0.46 0.01 0.38
E3
Glut 1 18.10 1.86 18.96 1.90 0.60 9.43 0.70 11.90 0.87 0.12
Glut 3 21.61 1.83 21.57 1.80 0.98 16.52 0.86 18.08 0.41 0.31
Glut 4 0.34 0.07 0.34 0.06 0.96 0.26 0.02 0.28 0.04 0.70
E4
Glut 1 10.37 1.40 10.45 0.79 0.96 10.43 1.31 11.21 1.28 0.65
Glut 3 18.55 1.01 18.71 0.86 0.92 19.90 0.85 21.34 1.36 0.40
Glut 4 0.27 0.02 0.39 0.04 0.03 0.38 0.05 0.39 0.08 0.93

Significant effects are indicated in bold.