Table 2.
Comparison of cerebrospinal fluid parameters between the two groups at four different time points after admission.
| Good outcome (n = 56) | Poor outcome (n = 25) | P-value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| CSF parameters (48 h) | |||||
| Lactate (mmol/L) | 4.57 | 1.55 | 7.02 | 2.44 | < 0.001 |
| ADA (U/L) | 5.64 | 3.62 | 7.45 | 3.97 | 0.047 |
| Chloride (mmol/L) | 112.8 | 7.5 | 110.0 | 6.9 | 0.121 |
| Protein (g/L) | 1.68 | 0.85 | 2.06 | 1.33 | 0.193 |
| Glucose (mmol/L) | 2.22 | 1.18 | 2.14 | 1.05 | 0.786 |
| Pressure (mmH2O) | 246.7 | 64.5 | 213.4 | 81.7 | 0.052 |
| CSF parameters (1 week) | |||||
| Lactate (mmol/L) | 3.75 | 1.04 | 4.67 | 1.47 | 0.008 |
| ADA (U/L) | 5.01 | 2.69 | 7.63 | 3.32 | < 0.001 |
| Chloride (mmol/L) | 115.8 | 5.3 | 111.4 | 6.2 | 0.001 |
| Protein (g/L) | 1.23 | 0.69 | 1.24 | 0.51 | 0.914 |
| Glucose (mmol/L) | 2.76 | 1.04 | 2.62 | 0.87 | 0.545 |
| Pressure (mmH2O) | 217.5 | 62.3 | 206.5 | 70.3 | 0.482 |
| CSF parameters (2 weeks) | |||||
| Lactate (mmol/L) | 3.33 | 1.00 | 4.08 | 1.22 | 0.005 |
| ADA (U/L) | 4.14 | 2.19 | 4.88 | 2.83 | 0.200 |
| Chloride (mmol/L) | 117.1 | 5.0 | 114.8 | 6.2 | 0.085 |
| Protein (g/L) | 0.94 | 0.37 | 1.14 | 0.67 | 0.177 |
| Glucose (mmol/L) | 2.91 | 1.22 | 2.91 | 1.00 | 0.985 |
| Pressure (mmH2O) | 210.6 | 62.6 | 189.0 | 58.0 | 0.147 |
| CSF parameters (3 weeks) | |||||
| Lactate (mmol/L) | 3.07 | 0.96 | 3.50 | 1.01 | 0.069 |
| ADA (U/L) | 3.33 | 1.92 | 4.35 | 2.61 | 0.052 |
| Chloride (mmol/L) | 118.7 | 5.0 | 116.4 | 5.8 | 0.075 |
| Protein (g/L) | 0.87 | 0.37 | 1.09 | 0.58 | 0.095 |
| Glucose (mmol/L) | 2.80 | 0.83 | 2.83 | 1.02 | 0.903 |
| Pressure (mmH2O) | 203.2 | 60.6 | 182.4 | 57.4 | 0.150 |
TBM, tuberculous meningitis; CSF, cerebrospinal fluid; ADA, adenosine deaminase.