Supplementary Table 1.

Organic and non-organic causes of behavioral change.^(4-7)

Vasculopathy	Cerebral ischemia and infarction Cerebral venous thrombosis Cerebral hemorrhage Moya Moya disease Hypertensive encephalopathy
Infective	Encephalitis Meningitis Brain abscesses HIV Neurosyphilis Tuberculous meningitis Toxoplasmosis Septic encephalopathy from other sources
Trauma	Traumatic brain injury Post-concussion syndrome
Autoimmune	SLE Multiple sclerosis Autoimmune encephalitis NMDA encephalitis Sjogren’s syndrome
Metabolic	Hypoglycemia Hyperglycemia Uremic encephalopathy Hepatic encephalopathy Vitamin B12 deficiency Hypercalcemia Hyponatremia Wilson’s disease Hypoxia Carbon monoxide poisoning Nitrogen narcosis from diving
Iatrogenic and Injury	Adverse drug reactions Drug-drug interactions Abrupt discontinuation of certain drugs Drug withdrawal Bites from venomous animals Lead poisoning
Neoplasm and	Primary brain tumors
Neurological	Metastasis to the brain Paraneoplastic syndrome Temporal lobe epilepsy Non convulsive seizure
Structural and Social	Raised intracranial pressure Normal pressure hydrocephalus Social deprivation Abuse and neglect Religious trance states and spirit possessions
Alcohol and other substance Abuse	Alcohol intoxication Korsakoff syndrome Delirium Tremens Wernicke encephalopathy Illicit drug abuse
Behavioral (Psychiatric conditions)	Psychotic disorder Schizoaffective disorder Mood disorders Bipolar disorder Psychosomatic disorders Post-traumatic stress disorder Acute grief response Adjustment disorder Peripartum mood, bipolar or psychotic disorders Dissociative disorders
Congenital and inherited conditions	Genetic conditions and syndromes Inherited conditions - Huntington’s disease, Wilson’s disease
Degenerative	Dementia - Alzheimer’s disease, vascular dementia, frontotemporal dementia, Lewy body dementia Parkinson disease
Endocrine	Hypothyroidism, myxedema coma Hyperthyroidism, thyroid storm Cushing’s syndrome Hyperparathyroidism

The above table of causes is non-exhaustive.