Table 3.
Univariate and multivariate analysis of cancer-specific survival (CSS) in the training set.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age (year) | 1.03 (1.02-1.03) | <0.001 | 1.02 (1.01-1.03) | <0.001 |
| Sex | ||||
| Female | 0.81 (0.65-1.01) | 0.062 | 0.90 (0.72-1.12) | 0.336 |
| Male | Reference | Reference | ||
| Race | ||||
| White | Reference | |||
| Black | 0.95 (0.69-1.31) | 0.755 | ||
| Others | 1.16 (0.78-1.71) | 0.460 | ||
| Marriage | ||||
| Married | Reference | |||
| Unmarried | 1.10 (0.87-1.37) | 0.437 | ||
| Grade | ||||
| I, II | Reference | Reference | ||
| III, IV | 1.69 (1.36-2.09) | <0.001 | 1.68 (1.34-2.11) | <0.001 |
| Tumour size (cm) | ||||
| ≤2 | Reference | Reference | ||
| 2-4 | 1.41 (0.99-2.00) | 0.050 | 1.40 (0.99-1.99) | 0.059 |
| >4 | 1.19 (0.84-1.69) | 0.332 | 1.20 (0.84-1.71) | 0.310 |
| T stage | ||||
| T1 | Reference | |||
| T2 | 1.01 (0.51-1.97) | 0.987 | ||
| T3 | 0.96 (0.56-1.64) | 0.876 | ||
| T4 | 1.14 (0.67-1.94) | 0.621 | ||
| N stage | ||||
| N0 | Reference | |||
| N1 | 1.06 (0.83-1.35) | 0.651 | ||
| N2 | 1.19 (0.87-1.62) | 0.280 | ||
| M stage | ||||
| M0 | Reference | |||
| M1 | 1.00 (0.68-1.49) | 0.987 | ||
| Radiotherapy | ||||
| Yes | 0.76 (0.54-1.05) | 0.094 | 1.03 (0.72-1.48) | 0.857 |
| No | Reference | Reference | ||
| Chemotherapy | ||||
| Yes | 0.76 (0.61-0.94) | 0.012 | 0.49 (0.38-0.64) | <0.001 |
| No | Reference | Reference | ||
| Lymph nodes removed | ||||
| <15 | Reference | Reference | ||
| ≥15 | 0.73 (0.58-0.91) | 0.006 | 0.77 (0.60-0.98) | 0.034 |
| LNR | ||||
| 0 | Reference | Reference | ||
| ≤0.47 | 1.98 (1.52-2.57) | <0.001 | 2.92 (2.18-3.90) | <0.001 |
| >0.47 | 3.66 (2.67-5.03) | <0.001 | 4.25 (3.01-6.00) | <0.001 |
LNR, lymph node ratio.