Fig. 2.

The hAPP695^SW transgene results in Aβ plaques, the area of which showed a positive correlation with fatty acyl carnitines. A) Immunohistochemistry staining for pan-Aβ of representative coronal sliced brain sections of WT (left) and Tg2576 (right) mice (one brain hemisphere). B) The horizontal bar graph visualizes the association between total Aβ plaque area (HA) (%) and 13 significantly correlated metabolites (at p ≤ 0.05 using Spearman rank correlation coefficients) in hippocampal tissue of Tg2576 mice.