FIG 9.
cspC is required for A. baumannii survival in a murine model of sepsis. Cohorts of BL/6 mice (n = 10) were inoculated by retroorbital injection with 2.5 × 107 CFU of wild-type (black) and cspC::tn mutant strains (blue). At 6 h postinfection, mice were euthanized, and organs were collected to determine bacterial load. The bounds of each box represent the 25th to 75th percentiles, whiskers represent the 5th to 95th percentiles, the center line denotes the median, and individual data points are plotted as circles. Statistical significance was determined using a Mann-Whitney nonparametric test. ***, P < 0.001; ****, P < 0.0001.