FIG 1.

MroQ is strongly conserved among S. aureus strains harboring Agr allelic variants. Comparison of the amino acid sequences of AgrB (A) and AgrD (B) in LAC (type I), SA502A (type II), MW2 (type III), and RN4850 (type IV). An underlined “IG” shows the conserved “helix breaker”; colored regions correspond to AIPs I to IV. Type I and IV AIPs peptides differ by 1 amino acid. (C) Amino acid sequence alignments of MroQ from LAC (type I), SA502A (type II), MW2 (type III), and RN4850 (type IV). Gray shading shows regions of dissimilarity. Underlined amino acids correspond to conserved active-site residues in MroQ.